The Diagram and extract below describes where HOT FLUSHES occur in the brain.

The Journal of Clinical Endocrinology & Metabolism, Volume 106, Issue
1, January 2021, Pages 1–15, https://doi.org/10.1210/clinem/dgaa764
In our brains, there’s a special group of cells called KNDy neurons that play a
key role in controlling hormone levels and body temperature. These neurons
are located in an area of the brain known as the hypothalamus and they work
with hormones like estrogen to regulate several functions.
KNDy neurons help manage the release of a hormone called GnRH, which is
important for reproductive health because it influences other hormones that affect the ovaries. These neurons also have a role in regulating body heat, which is why they’re linked to the hot flushes often experienced during
menopause.
During menopause, as women transition with age, the usual way these
neurons work can change. They might not respond to estrogen as they did before, and their usual signaling might become stronger or different. This
change is believed to contribute to the hot flushes many women experience
at times.
By understanding how these neurons work, we can gain insights into managing menopausal symptoms better.
Learn More at https://menopause-and-you.com


Leave a comment